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Products > Apoptosis > Bcl-2 inhibitor > A-1210477 (A1210477)
A-1210477 (A1210477)
Product name : A-1210477 (A1210477)
Product No. : cc-2202
Price : 100mg, $475, 500mg/$1275
CAS : 
Bulk inquiry : 
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  Details:
 A-1210477 (CAS: 1668553-26-1) is an inhibitor of MCL-1 (Ki=0.45 nM in TR-FRET-binding assays), is a much weaker binder of BCL-2 (Ki=0.132 μM) and BCL-XL(Ki>0.660 μM).  A-1210477 induces the hallmarks of intrinsic apoptosis and demonstrates single agent killing of multiple myeloma and non-small cell lung cancer cell lines.

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