TGF-beta/Smad
PTEN
|
Product name : ON123300 (ON-123300)
Product No. : cs-2199
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
|
| Details: |
ON123300 (CAS: 1357470-29-1 ) is a potent multikinase inhibitor and may be potential useful for brain tumor chemotherapy. ON123300 strongly inhibits Ark5 and CDK4, as well as growth factor receptor tyrosine kinases such as β-type platelet-derived growth factor receptor (PDGFRβ). ON123300 inhibits U87 glioma cell proliferation with an IC(50) 3.4 ± 0.1 μmol/L. ON123300 exhibits potent activity against mantle cell lymphomas (MCLs) both in vitro and in vivo. ON123300 might be an effective agent in MCL, including ibrutinib-resistant forms of the disease.
|
| Related Products : |
|
|
|
|
||||||||
|
|
|
|
