TGF-beta/Smad
Histone Methyltransferase
|
Product name : LGK-974 (LGK974, LGK 974)
Product No. : cs-1102
Price : 100mg, $675, 500mg/$1875
CAS :
Bulk inquiry :
|
| Details: |
LGK-974 (CAS: 1243244-14-5) is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM. Porcupine, a membrane-bound O-acyltransferase (MBOAT), is required for the palmitoylation of Wnt ligands, and plays a key role in Wnt ligand secretion and activity. Wnt signaling is dysregulated in a variety of cancers.
|
| Related Products : |
|
|
|
|
||||||||
|
