Product name : Alvelestat (AZD9668; AZD-9668; AZD 9668)
Product No. : cs-1060
Price : 100mg, $675, 500mg/$1875
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Alvelestat (CAS: 848141-11-7) is a novel, oral inhibitor of neutrophil elastase (NE) with the pIC50 of 7.9 for Human NE. Neutrophil elastase (NE) is an enzyme implicated in the signs, symptoms, and disease progression in NE-driven respiratory diseases such as bronchiectasis and chronic obstructive pulmonary disease via its role in the inflammatory process, mucus overproduction, and lung tissue damage.
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