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Products > Cell Cycle/DNA Damage > p21-activated Kinases (PAKs) > PF-3758309 (PF 3758309; PF3758309)
PF-3758309 (PF 3758309; PF3758309)
Product name : PF-3758309 (PF 3758309; PF3758309)
Product No. : cs-1014
Price : 100mg, $475, 500mg/$1275
CAS : 
Bulk inquiry : 
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  Details:
PF-3758309 (CAS: 898044-15-0 (free base); 1279034-84-2 (HCl)) is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PAK4 inhibitor PF-03758309 binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.

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