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C-646 (C646, C 646)
Product name : C-646 (C646, C 646)
Product No. : cs-1006
Price : 100mg, $475, 500mg/$1275
CAS : 
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C646 (CAS: 328968-36-1) is a selective competitive histone acetyltransferase p300 inhibitor with Ki of 400 nM. C646 induces cell cycle arrest and apoptosis selectively in AML1-ETO-positive AML cells. C646 radiosensitizes lung cancer cells by enhancing mitotic catastrophe. C646 reverses epithelial to mesenchymal transition of human peritoneal mesothelial cells via blocking TGF-β1/Smad3 signaling pathway in vitro

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