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Products > Cell Cycle/DNA Damage > PLK > Ro-3280 (RO-3280; RO 3280; Ro5203280; Ro-5203280; Ro 5203280)
Ro-3280 (RO-3280; RO 3280; Ro5203280; Ro-5203280; Ro 5203280)
Product name : Ro-3280 (RO-3280; RO 3280; Ro5203280; Ro-5203280; Ro 5203280)
Product No. : cs-992
Price : 100mg, $675, 500mg/$1875
CAS : 
Bulk inquiry : 
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  Details:
RO3280 (CAS: 1062243-51-9) is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM. RO3280 treatment regulated several apoptosis-associated genes. Polo-like kinase 1 (PLK1) is highly expressed in many cancers and therefore a biomarker of transformation and potential target for the development of cancer-specific small molecule drugs.

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