TGF-beta/Smad
VEGFR
Products > Protein Tyrosine Kinase/RTK > c-Met inhibitor > Tepotinib (EMD-1214063, EMD1214063, EMD 1214063)
|
Product name : Tepotinib (EMD-1214063, EMD1214063, EMD 1214063)
Product No. : cs-977
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
|
| Details: |
EMD 1214063 (CAS: 1100598-32-0) is a potent and selective c-Met inhibitor with IC50 of 4 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. EMD 1214063 selectively binds to MET tyrosine kinase and disrupts MET signal transduction pathways, which may induce apoptosis in tumor cells overexpressing this kinase.
|
| Related Products : |
|
|
|
|
||||||||
|
|
|
|
