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Products > Apoptosis > MDM-2, p53 > NVP-CGM097 (CGM097; CGM 097; CGM-097; NVP CGM097)
NVP-CGM097 (CGM097; CGM 097; CGM-097; NVP CGM097)
Product name : NVP-CGM097 (CGM097; CGM 097; CGM-097; NVP CGM097)
Product No. : cs-2423
Price : 100mg, $975, 500mg/$2475
CAS : 
Bulk inquiry : 
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  Details:
NVP-CGM097 (CAS: 1313363-54-0) is a potent and selective MDM2 inhibitor with IC50 of 1.7±0.1 nM for hMDM2 By preventing this HDM2-p53 interaction, the proteosome-mediated enzymatic degradation of p53 is inhibited, which may result in the restoration of p53 signaling and, thus, the p53-mediated induction of tumor cell apoptosis. 

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