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Products > JAK/STAT Signaling > EGFR > AV-412 (AV412. AV 412, MP-412, MP412))
AV-412 (AV412. AV 412, MP-412, MP412))
Product name : AV-412 (AV412. AV 412, MP-412, MP412))
Product No. : cs-2307
Price : 100mg, $675, 500mg/$1875
CAS : 
Bulk inquiry : 
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  Details:
MP 412 (CAS: 451492-95-8) is a potent dual inhibitor of EGFR and ErbB2(IC50=19 nM) tyrosine kinases, including the mutant EGFR(L858R IC50=0.51 nM, T790M IC50=0.79 nM); inhibits autophosphorylation of EGFR and ErbB2 with IC(50) of 43 and 282 nM, respectively.

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