TGF-beta/Smad
PTEN
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Product name : CC-223 (CC223)
Product No. : cs-2163
Price : 100mg, $675, 500mg/$1475
CAS : 1228013-30-6)
Bulk inquiry : contact sales@cckinase.com for bulk inquiry
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CC-223 (CAS:1228013-30-6) is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity over the related lipid kinase PI3Kα (IC50=4 μM). mTOR, a serine/threonine kinase that is upregulated in a variety of tumors, plays an important role downstream in the PI3K/AKT/mTOR signaling pathway, which is frequently dysregulated in human cancers.
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