Product name : GDC-0853 (GDC0853, GDC 0853)
Product No. : cs-2241
Price : 100mg, $975, 500mg/$2475
CAS :
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GDC-0853 (CAS: 1434048-34-6) inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. BTK, a member of the Src-related BTK/Tec family of cytoplasmic tyrosine kinases, is overexpressed in B-cell malignancies; it plays an important role in B-lymphocyte development, activation, signaling, proliferation and survival.
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