TGF-beta/Smad
EZH2
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Product name : GSK-J4
Product No. : cs-2143
Price : 100mg, $475, 500mg/$1275
CAS :
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| Details: |
GSK J4 (CAS: 1373423-53-0) is a cell permeable prodrug rapidly hydrolyzed by macrophage esterases to GSK-J1, a potent selective jumonji H3K27 demethylase inhibitor; attenuates lipopolysaccharide (LPS)-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 μM for the inhibition of TNFα release).
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