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AF-353 (AF353, AF 353)
Product name : AF-353 (AF353, AF 353)
Product No. : 20171225313
Price : 100mg/$475; 500mg/$1275
CAS : 
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AF-353 (CAS: 865305-30-2) is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, inhibits human and rat P2X3 (pIC50= 8.0).  Antagonism of the P2X3 receptor is one of the potential therapeutic strategies for the management of neuropathic pain because P2X3 receptors are predominantly localized on small to medium diameter C- and Aδ-fiber primary afferent neurons,

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