Product name : Ipatasertib (GDC-0068, GDC0068, GDC 0068)
Product No. : 2018928102126
Price : 10mg/$125; 100mg/$675; 500mg/$1875
CAS : 1001264-89-6 (free base) 1489263-16-2 (HCl)
Bulk inquiry : contact sales@cckinase.com for bulk inquiry
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GDC-0068 (10mg/$125; 100mg/$675, CAS: 1001264-89-6) is a highly selective pan-Akt inhibitor targeting Akt1/Akt2/Akt3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA. Akt inhibitor GDC-0068 binds to and inhibits the activity of Akt in a non-ATP-competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.
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