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Products > Metabolic enzyme/Protease > MMP Inhibitor > KP-457 (KP457, KP 457)
KP-457 (KP457, KP 457)
Product name : KP-457 (KP457, KP 457)
Product No. : 20181213234424
Price : 100mg/$1275
CAS : 1365803-52-6
Bulk inquiry : contact sales@cckinase.com for bulk inquiry
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  Details:
KP-457 (CAS: 1365803-52-6) is a selective a disintegrin and metalloproteinase 17 (ADAM17) inhibitor, with higher selectivity for ADAM17 than for other MMPs and ADAM10, and IC50s are 11.1 nM (ADAM17), 748 nM (ADAM10), 717 nM (MMP2), 9760 nM (MMP3), 2200 nM (MMP8), 5410 nM (MMP9), 930 nM (MMP13), 2140 nM (MMP14), and 7100 nM (MMP17), respectively.

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