TGF-beta/Smad
Sodium Channel
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Product name : Eliprodil(SL-820715, SL820715)
Product No. : cs-2114
Price : 100mg, $675, 500mg/$1874
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| Details: |
Eliprodil(SL 820715) is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM). NMDA receptors are a key component in mediating glutamate-induced excitotoxicity, and it is believed that NMDA antagonists would be neuroprotective after a stroke or other traumatic brain injury. Eliprodil protects pyramidal neurons in hippocampal slices from hypoxic/ischemic damage. Eliprodil stimulates CNS myelination, may be a new prospect for multiple sclerosis.
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