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Products > Others > Others > BVT-273 (BVT2733)
BVT-273 (BVT2733)
Product name : BVT-273 (BVT2733)
Product No. : cs-2111
Price : 100mg, $475, 500mg/$975
CAS : 376640-41-4)
Bulk inquiry : 
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  Details:
 BVT 2733 (CAS: 376640-41-4) is a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor, which attenuates obesity and inflammation in diet-induced obese mice. BVT-2733 protects osteoblasts against endogenous glucocorticoid induced dysfunction. BVT-2733 exhibits an anti-inflammatory effect on CIA. This protective effect is, at least partly, mediated by inhibition of the NF-κB and NLRP1 inflammasome signaling pathways. 11β-Hydroxysteroid dehydrogenase 1 (11β-HSD1) plays an important role in inflammation. 11β-HSD1 inhibition may represent a potential therapeutic target for RA patients.

Technical Data

Appearance:

Off White Solid

Purity:

> 98%

QC Data:

View Current Lot Data File

CAS:

376640-41-4)

Storage

-20°C, long term; 4°C, short term

Shipping

Room temperature


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