TGF-beta/Smad
VEGFR
Products > Protein Tyrosine Kinase/RTK > c-FMS > Edicotinib (JNJ-40346527, JNJ40346527, JNJ 40346527)
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Product name : Edicotinib (JNJ-40346527, JNJ40346527, JNJ 40346527)
Product No. : 202071110923
Price : 100mg/$675; 500mg/$1875
CAS : 1142363-52-7
Bulk inquiry : contact sales@cckinase.com for bulk inquiry
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Edicotinib (CAS: 1142363-52-7) blocks the receptor-ligand interaction between FMS and its ligand CSF1, thereby preventing autophosphorylation of FMS. As a result, unphosphorylated FMS cannot activate FMS-mediated signaling pathways, thus potentially inhibiting cell proliferation in FMS-overexpressed tumor cells.
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