Product name : Tozadenan (SYN-115, SYN115, SYN 115)
Product No. : 202072311325
Price : 100mg $475, 500mg/$1275
CAS : 870070-55-6
Bulk inquiry : contact sales@cckinase.com for bulk inquiry
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Tozadenant (CAS: 870070-55-6) is an adenosine A2A receptor antagonist, with Ki of 11.5 nM on human A2A and 6 nM on rhesus A2A. Adenosine A(2a) receptor antagonists reduce symptom severity in Parkinson disease (PD) and animal models. Rodent studies support the hypothesis that A(2a) antagonists produce this benefit by reducing the inhibitory output of the basal ganglia indirect pathway.
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