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Products > Membrane Transporter/Ion Channel > TRP Channel > Chembridge-5861528 (TCS5861528; TCS-5861528)
Chembridge-5861528 (TCS5861528; TCS-5861528)
Product name : Chembridge-5861528 (TCS5861528; TCS-5861528)
Product No. : cs-2103
Price : 100mg, $475, 500mg/$1275
CAS : 
Bulk inquiry : 
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  Details:
 Chembridge 5861528 (CAS: 332117-28-9 )is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx (IC50 values are 14.3 and 18.7μM respectively). TRPA1 was found to mediate acute inflammation and the development of degenerative cartilage changes and joint pain in MIA-induced experimental OA in the mouse. TRPA1 may be a potential mediator and drug target in OA.

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