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Products > Cell Cycle/DNA Damage > EZH2 > EPZ-011989 (EPZ011989)
EPZ-011989 (EPZ011989)
Product name : EPZ-011989 (EPZ011989)
Product No. : cs-2079
Price : 100mg, $475, 500mg/$1275
CAS : 
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  Details:
 EPZ011989 (CAS:1598383-40-4) is a potent, selective orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 wt and EZH2 Y646; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase.  Inhibitors of the protein methyltransferase Enhancer of Zeste Homolog 2 (EZH2) may have significant therapeutic potential for the treatment of B cell lymphomas and other cancer indications.

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