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Products > Others > Others > NCT-501 (NCT501)
NCT-501 (NCT501)
Product name : NCT-501 (NCT501)
Product No. : cs-2069
Price : 50mg, $675; 100mg, $1175
CAS : 
Bulk inquiry : 
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  Details:
 NCT 501 (CAS: 1802088-50-1)is a potent and selective theophylline-based inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), inhibits hALDH1A1 with IC50 of 40 nM, typically shows better selectivity over other ALDH isozymes and other dehydrogenases (hALDH1B1, hALDH3A1, and hALDH2, IC50 >57 μM). Increased ALDH (e.g., ALDH1A1) gene expression and catalytic activity are vital biomarkers in a number of malignancies and cancer stem cells, highlighting the need for the identification and development of small molecule ALDH inhibitors.

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