TGF-beta/Smad
GPR109A
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Product name : MK-5046 (MK5046)
Product No. : cs-2034
Price : 50mg, $675; 100mg, $1175
CAS :
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| Details: |
MK 5046 (CAS: 1022152-70-0) is a novel BRS-3 agonist, binds to BRS-3 with high affinity (mouse Ki = 1.6 nM, human Ki = 25 nM). MK-5046 is the first BRS-3 agonist with properties suitable for use in larger mammals. In dogs, MK-5046 treatment produced statistically significant and persistent weight loss, which was initially accompanied by increases in body temperature and heart rate that abated with continued dosin
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