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Products > Protein Tyrosine Kinase/RTK > CSF-1R inhibitor > JNJ-28312141 (JNJ28312141)
JNJ-28312141 (JNJ28312141)
Product name : JNJ-28312141 (JNJ28312141)
Product No. : cs-2012
Price : 100mg, $675, 500mg/$1875
CAS : 
Bulk inquiry : 
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  Details:
 JNJ 28312141 (CAS: 885692-52-4) is an orally active CSF1R inhibitor (Colony-stimulating factor-1 receptor, CRF1R) and also a FLT3 inhibitor. CSF1R is expressed by many tumors and is a growth factor for macrophages and mediates osteoclast differentiation. JNJ-28312141 represents a new agent with potential therapeutic activity in acute myeloid leukemia and in settings where CSF-1-dependent macrophages and osteoclasts contribute to tumor growth and skeletal events.

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