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Products > TGF-beta/Smad > PKC > Enzastaurin (LY317615, LY-317615)
Enzastaurin (LY317615, LY-317615)
Product name : Enzastaurin (LY317615, LY-317615)
Product No. : cs-1980
Price : 50mg, $675; 100mg, $1175
CAS : 
Bulk inquiry : 
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  Details:
LY 317615 (CAS: 170364-57-5) is a potent PKCβ selective inhibitor with IC50 of 6 nM, 6- to 20-fold selectivity against PKCα, PKCγ and PKCε.  Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden. 

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