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Products > GPCR/G protein > mGluR > VU-0357121 (VU0357121)
VU-0357121 (VU0357121)
Product name : VU-0357121 (VU0357121)
Product No. : cs-1971
Price : 100mg, $475, 500mg/$1275
CAS : 
Bulk inquiry : 
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  Details:
 VU 0357121 (CAS: 433967-28-3) is a novel positive and highly selective allosteric modulator (PAM) of mGlu5R with EC50 of 33 nM. Mutagenesis studies indicate that VU0357121 and related analogues bind to a yet uncharacterized allosteric site on mGlu(5), distinct from CPPHA, yet share a functional interaction with the MPEP site.

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