TGF-beta/Smad
VEGFR
|
Product name : PF-04217903 (PF04217903)
Product No. : cs-1921
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
|
| Details: |
PF 04217903 (CAS: 956905-27-4 (free base); 956906-93-7 (mesylate)) is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susceptible to oncogenic mutations (no activity to Y1230C mutant). PF-04217903 binds to and inhibits c-Met, disrupting the c-Met signaling pathway, which may result in the inhibition of tumor cell growth, migration and invasion of tumor cells, and the induction of death in tumor cells expressing c-Met.
|
| Related Products : |
|
|
|
|
||||||||
|
|
|
|
