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Products > Membrane Transporter/Ion Channel > CFTR > Ivacaftor (VX-770; VX 770; VX770; Kalydeco)
Ivacaftor (VX-770; VX 770; VX770; Kalydeco)
Product name : Ivacaftor (VX-770; VX 770; VX770; Kalydeco)
Product No. : cs-1914
Price : 100mg, $475, 500mg/$1275
CAS : 
Bulk inquiry : 
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  Details:
 VX-770 (CAS: 873054-44-5) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively.  VX-770 increases the probability that the defective channel will be open and allow chloride ions pass through the channel pore. 

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