Product name : Ivacaftor (VX-770; VX 770; VX770; Kalydeco)
Product No. : cs-1914
Price : 100mg, $475, 500mg/$1275
CAS :
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Details: |
VX-770 (CAS: 873054-44-5) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively. VX-770 increases the probability that the defective channel will be open and allow chloride ions pass through the channel pore.
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