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Products > Stem cell signaling > Hedgehog > Vismodegib (GDC-0449; GDC 0449; GDC0449)
Vismodegib (GDC-0449; GDC 0449; GDC0449)
Product name : Vismodegib (GDC-0449; GDC 0449; GDC0449)
Product No. : cs-1913
Price : 50mg, $675; 100mg, $1175
CAS : 
Bulk inquiry : 
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 Vismodegib (CAS: 879085-55-9) is a more potent novel and specific synthetic oral hedgehog pathway inhibitor with an IC50 of 3 nM; also inhibits P-gp with IC50 of 3.0 μM. Hedgehog antagonist GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling.

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