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Products > NF-KB > IKK > BMS-345541 (BMS345541)
BMS-345541 (BMS345541)
Product name : BMS-345541 (BMS345541)
Product No. : cs-1910
Price : 100mg, $675, 500mg/$1875
CAS : 
Bulk inquiry : 
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  Details:
 BMS 345541 (CAS: 445430-58-0 (free base); 547757-23-3 (HCl)) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively. It attenuates LPS-induced cytokine production in vitro and blocks NFκB dependent transcription in mice. BMS 345541 also suppresses joint destruction in a mouse model of arthritis.

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