TGF-beta/Smad
Nampt
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Product name : AGI-6780 (AGI6780)
Product No. : cs-1905
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
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| Details: |
AGI 6780 (CAS: 1432660-47-3) is the first highly potent and selective small molecule inhibitor of isocitrate dehydrogenases, which binds in an allosteric manner at the dimer interface of mutant IDH2-R140Q (IC50=23 nM). Inhibitors targeting mutant IDH2/R140Q could have potential applications as a differentiation therapy for cancer.
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