TGF-beta/Smad
Phospholipase
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Product name : IU1 (IU-1)
Product No. : cs-1901
Price : 100mg, $675, 500mg/$1875
CAS :
Bulk inquiry :
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| Details: |
IU 1 (CAS: 314245-33-5)is a selective USP14 inhibitor. IU1 prevents ventilator-induced lung injury in rats. IU1 inhibits the catalytic activity of proteasome-associated Usp14 in vitro (IC50 < 4 μM). IU1 stimulates proteasome activity and substrate degradation. USP14 removes the ubiquitin chain of I-κB, therefore inducing I-κB degradation and increasing cytokine release
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