TGF-beta/Smad
Nampt
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Product name : Bortezomib (PS-341; Velcade; PS341; PS 341)
Product No. : cs-1886
Price : 500mg, $675
CAS :
Bulk inquiry :
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| Details: |
Bortezomib (CAS; 179324-69-7) is a potent 20S proteasome inhibitor with Ki of 0.6 nM. Bortezomib reversibly inhibits the 26S proteasome, a large protease complex that degrades ubiquinated proteins. By blocking the targeted proteolysis normally performed by the proteasome, bortezomib disrupts various cell signaling pathways, leading to cell cycle arrest, apoptosis, and inhibition of angiogenesis.
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