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Products > GPCR/G protein > 5-HT Receptor > SB-271046 (SB271046)
SB-271046 (SB271046)
Product name : SB-271046 (SB271046)
Product No. : cs-1869
Price : 100mg, $675, 500mg/$1875
CAS : 
Bulk inquiry : 
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  Details:
 SB 271046 HCl (CAS: 209481-24-3 (HCl); 209481-20-9 (free base)) is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9. SB-271046 was found to increase levels of the excitatory amino acid neurotransmitters glutamate and aspartate, as well as dopamine and noradrenaline in the frontal cortex and hippocampus of rats, and 5-HT6 antagonists have been shown to produce nootropic effects in a variety of animal studies. Suggested applications of these drugs include treatment of schizophrenia and other psychiatric disorders. 

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