TGF-beta/Smad
MNK
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Product name : GDC-0994 (Ravoxertinib, GDC0994, RG-7842, RG7842)
Product No. : cs-1841
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
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| Details: |
GDC 0994 (CAS: 1453848-26-4) is highly selective for ERK1 and ERK2, with biochemical potency of 1.1 nM and 0.3 nM, respectively. This prevents ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.
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