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Products > Cell Cycle/DNA Damage > Topoisomerase > Genz-644282 (GENZ644282)
Genz-644282 (GENZ644282)
Product name : Genz-644282 (GENZ644282)
Product No. : cs-1079
Price : 100mg, $675, 500mg/$1475
CAS : 
Bulk inquiry : 
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  Details:
 Genz-644282 (CAS: 529488-28-6) is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity(IC50=1.2 nM). Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations.

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