TGF-beta/Smad
PTEN
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Product name : CHIR-98014 (CHIR98014; CHIR 98014)
Product No. : cs-1797
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
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| Details: |
CHIR-98014 (CAS: 556813-39-9) is a selective GSK3 inhibitor with IC50s of 0.65 nM and 0.58 nM for GSK-3α and GSK-3β; potentiate insulin activation of glucose transport and utilization in vitro and in vivo. CHIR98014 stimulates glycogen synthase in cells (EC50 = 106 nM), potentiates insulin-dependent glucose transport in isolated muscle strips, and improves glucose disposal in diabetic animals.
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