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Products > Others > Others > GKT-137831 (GKT 137831; GKT137831)
GKT-137831 (GKT 137831; GKT137831)
Product name : GKT-137831 (GKT 137831; GKT137831)
Product No. : cs-1795
Price : 100mg, $675, 500mg/$1875
CAS : 
Bulk inquiry : 
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  Details:
GKT137831 (CAS: 1218942-37-0, 100mg, $675, 500mg/$1875) is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 140±40 nM and 110±30 nM; a potent inhibitor of fibrosis and hepatocyte apoptosis. GKT137831 reduced the increased leukocyte adherence to the vasculature, the pro-inflammatory phenotype of microglia a, nd macroglia, the increased gene and protein expression of vascular endothelial growth factor, monocyte chemoattractant protein-1, and leukocyte adhesion molecules as well as vascular leakage.  

Technical Data

Appearance:

Off White Solid

Purity:

> 98%

QC Data:

View Current Lot Data File

CAS:

1437321-24-8

Storage

-20°C, long term; 4°C, short term

Shipping

Room temperature


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