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Products > MAPK/ERK Pathway > Mixed Lineage Kinase > URMC-099 (URMC099, URMC 099)
URMC-099 (URMC099, URMC 099)
Product name : URMC-099 (URMC099, URMC 099)
Product No. : cs-1776
Price : 100mg, $475, 500mg/$1275
CAS : 
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  Details:
 URMC-099 (CAS: 1229582-33-5) is an orally bioavailable, brain penetrant inhibitor of Mixed Lineage Kinase 3(MLK3) with IC50 of 14 nM. It inhibits LPS-induced TNFα release in microglial cells, HIV-1 Tat-induced release of cytokines in human monocytes, and up-regulation of phospho-JNK in Tat-injected brains of mice.

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