TGF-beta/Smad
MNK
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Product name : LJI308 (LJI-308)
Product No. : 2016612224
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
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| Details: |
LJI308 (CAS: 1627709-94-7) is a new and potent pan-RSK inhibitor, with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 overcomes chemoresistance by eliminating cancer stem cells. LJI308 targets the CSC population and repress TNBC growth and dissemination. LJI308 specifically targeted transformed cells as it had little effect on the non-tumorigenic parental HMECs
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