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Products > Others > DNA/RNA Synthesis > BMH-21 (BMH21, BMH 21)
BMH-21 (BMH21, BMH 21)
Product name : BMH-21 (BMH21, BMH 21)
Product No. : cs-1749
Price : 100mg, $475, 500mg/$1275
CAS : 
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  Details:
 BMH-21 (CAS: 896705-16-1) binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription. BMH-21 does not cause phosphorylation of H2AX, a key biomarker activated in DNA damage stress. BMH-21 effects on the nucleolar stress response were independent of major DNA damage associated PI3-kinase pathways, ATM, ATR and DNA-PKcs. BMH-21 is a chemically unique DNA intercalator that has high bioactivity towards Pol I inhibition without activation or dependence of DNA damage stress. 

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