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Products > GPCR/G protein > Neuropeptide Y receptor > JNJ-31020028 (JNJ31020028, JNJ 31020028)
JNJ-31020028 (JNJ31020028, JNJ 31020028)
Product name : JNJ-31020028 (JNJ31020028, JNJ 31020028)
Product No. : cs-1745
Price : 100mg, $475, 500mg/$1275
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 JNJ-31020028 (CAS: 1094873-14-9) is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22 rat); >100-fold selective versus human Y1/Y4/Y5 receptors. JNJ-31020028 increased norepinephrine release in the hypothalamus, consistent with the colocalization of norepinephrine and neuropeptide Y.  

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