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Products > Cell Cycle/DNA Damage > PLK > TAK-960 (TAK960, TAK 960)
TAK-960 (TAK960, TAK 960)
Product name : TAK-960 (TAK960, TAK 960)
Product No. : cs-1725
Price : 100mg, $475, 500mg/$1275
CAS : 
Bulk inquiry : 
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  Details:
 TAK-960(CAS: 1137868-52-0) is a novel, investigational, orally bioavailable, potent, and selective PLK1 inhibitor(IC50=1.5 nM) that has shown activity in several tumor cell lines, including those that express multidrug-resistant protein 1 (MDR1). TAK-960 selectively inhibits PLK1, inducing selective G2/M cell-cycle arrest followed by apoptosis in a variety of tumor cells while causing reversible cell-cycle arrest at the G1 and G2 stages without apoptosis in normal cells.

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