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SEA0400 (SEA-0400)
Product name : SEA0400 (SEA-0400)
Product No. : 201661642233
Price : 100mg, $475, 500mg/$1275
CAS : 
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 SEA0400 (CAS: 223104-29-8)  is a novel and selective inhibitor of the Na+-Ca2+ exchanger with IC50 of 5-33 nM (inhibiting Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia). SEA0400 reduces calcium overload induced by ischemia and reperfusion in mouse ventricular myocytes. SEA0400 attenuates sodium nitroprusside-induced apoptosis in cultured rat microglia. SEA0400, preserves cardiac function and high-energy phosphates against ischemia/reperfusion injury.

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