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KB-R7943 (KBR7943)
Product name : KB-R7943 (KBR7943)
Product No. : 201661642539
Price : 100mg, $475, 500mg/$1275
CAS : 
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 KB-R7943 (CAS: 182004-65-5) is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 μM). KB-R7943 does not modify secondary pathology in the thalamus following focal cerebral stroke in rats. KB-R7943 blocks opening of the mitochondrial permeability transition pore. KB-R7943 restores endothelium-dependent relaxation induced by advanced glycosylation end products in rat aorta. KB-R7943 inhibits high glucose-induced endothelial ICAM-1 expression and monocyte-endothelial adhesion.

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