cckinase, Inc.

Favorite  |  Set Home
E-mail: info@cckinase.com
Products > Others > DNA/RNA Synthesis > TH-588 (TH588, TH 588)
TH-588 (TH588, TH 588)
Product name : TH-588 (TH588, TH 588)
Product No. : cs-1701
Price : 500mg, $875
CAS : 
Bulk inquiry : 
←[Previous Product]              [Next Product]→
Online Inquiry         Email Us

  Details:
 TH588 (CAS: 1609960-31-7) is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1(IC50= 5 nM) in cells.  Cancers have dysfunctional redox regulation resulting in reactive oxygen species production, damaging both DNA and free dNTPs. The MTH1 protein sanitizes oxidized dNTP pools to prevent incorporation of damaged bases during DNA replication. 

  Related Products :

CX-5461 (CX5461)
CX-5461 (CX5461)
Price: 100mg, $475, 500mg/$1275

BMH-21 (BMH21, BMH 21)
BMH-21 (BMH21, BMH 21)
Price: 100mg, $475, 500mg/$1275

TH-287 (TH287)
TH-287 (TH287)
Price: 100mg, $475, 500mg/$1275

TH-287 (TH287, TH 287)
TH-287 (TH287, TH 287)
Price: 100mg, $475, 500mg/$1275

SCR-7 (SCR7, SCR 7)
SCR-7 (SCR7, SCR 7)
Price: 100mg, $475, 500mg/$1275

Online service

info@cckinase.com