Products > Protein Tyrosine Kinase/RTK > c-Met inhibitor > Altiratinib (DCC2701; DCC 2701; DCC-2701; DP 5164; DP5164; DP-5164)
Product name : Altiratinib (DCC2701; DCC 2701; DCC-2701; DP 5164; DP5164; DP-5164)
Product No. : cs-1690
Price : 100mg, $475, 500mg/$1275
CAS :
Bulk inquiry :
|
Details: |
Altiratinib (CAS: 1345847-93-9) is an oral, selective and highly potent inhibitor of MET, TIE2, VEGFR2 and TRK kinases with potential anticancer activity. DCC-2701 effectively reduces tumor burden in vivo and blocks c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro. Importantly, DCC-2701's anti-proliferative activity was dependent on c-MET activation induced by stromal human fibroblasts and to a lesser extent exogenous HGF.
|
Related Products : |
|
|
|
|
||||||||
|
|
|
|