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Products > Cell Cycle/DNA Damage > Microtubule/Tubulin > Cevipabulin (TTI-237, TTI 237, TTI237)
Cevipabulin (TTI-237, TTI 237, TTI237)
Product name : Cevipabulin (TTI-237, TTI 237, TTI237)
Product No. : cs-1680
Price : 100mg, $675, 500mg/$1875
CAS : 
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  Details:
 Cevipabulin (CAS: 849550-05-6 (free base); 852954-81-5) is a small synthetic molecule of triazolopyrimidine derivative with potential antitumor activity. With a novel mechanism of action distinct from the action of other vinca alkaloid compounds, TTI-237 specifically binds to tubulin at the vinca site, and promotes the polymerization of tubulin into microtubules. TTI-237 stabilizes tubulin and inhibits microtubule disassembly. This results in cell cycle arrest at the G2/M phase, and leading to cell death. Check for active clinical trials or closed clinical trials using this agent.

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