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Products > Membrane Transporter/Ion Channel > TRP Channel > Mavatrep (JNJ-39439335, JNJ39439335, JNJ 39439335)
Mavatrep (JNJ-39439335, JNJ39439335, JNJ 39439335)
Product name : Mavatrep (JNJ-39439335, JNJ39439335, JNJ 39439335)
Product No. : cs-1660
Price : 100mg, $975, 500mg/$2475
CAS : 
Bulk inquiry : 
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  Details:
 Mavatrep (CAS: 956274-94-5) is an orally bioavailable TRPV1 antagonist (Ki=6.5 nM), exhibits minimal effect on the enzymatic activity (IC50 > 25 μM) of CYP isoforms 3A4, 1A2, and 2D6. On the basis of its superior pharmacologic and safety profile, Mavatrep was selected for clinical development for the treatment of pain. 

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