TGF-beta/Smad
Sodium Channel
Products > Membrane Transporter/Ion Channel > TRP Channel > Mavatrep (JNJ-39439335, JNJ39439335, JNJ 39439335)
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Product name : Mavatrep (JNJ-39439335, JNJ39439335, JNJ 39439335)
Product No. : cs-1660
Price : 100mg, $975, 500mg/$2475
CAS :
Bulk inquiry :
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| Details: |
Mavatrep (CAS: 956274-94-5) is an orally bioavailable TRPV1 antagonist (Ki=6.5 nM), exhibits minimal effect on the enzymatic activity (IC50 > 25 μM) of CYP isoforms 3A4, 1A2, and 2D6. On the basis of its superior pharmacologic and safety profile, Mavatrep was selected for clinical development for the treatment of pain.
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